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PRINCIPAL INVESTIGATOR / PhD

Tom Vanden Berghe

Tom Vanden Berghe obtained his Master's and PhD in Science (Biotechnology) in 1999 and 2005, respectively. Following his doctoral studies, he pursued postdoctoral research at the VIB-UGent Center for Inflammation Research. In 2018, he was appointed as an Assistant Professor at the University of Antwerp and Guest Professor at Ghent University. He was promoted to Associate Professor in 2023 and, through a fast-track procedure, achieved the rank of Professor in 2024.

Professor Vanden Berghe is head of the Cell Death Signaling Lab at University of Antwerp. His mission is to conduct applied research focusing on cell death, particularly ferroptosis, pyroptosis (inflammation), and associated diseases. The Vanden Berghe Lab investigates mechanisms, diagnostics, and intervention strategies related to critical illnesses, brain injuries, kidney and vascular diseases. In addition, the team explores the potential of ferroptosis as a novel anti-cancer therapy for eliminating therapy-resistant cancers. Professor Vanden Berghe has established a comprehensive ferroptosis platform encompassing novel lead ferroptosis inhibitors and genes, ferroptosis diagnostics, and ferroptosis-based nanomedicine for anti-cancer therapeutics.

meet our team

Lab members

University of Antwerp
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Tom Vanden Berghe, PhD

PRINCIPAL INVESTIGATOR

Professor @ UAntwerp
Guest Professor @ UGent

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Anja Verhulst, PhD

Team leader

Research coordinator
10% ZAP
Vascular calcification

2011 Benjamin Vervaet MR

Benjamin Vervaet, PhD

Team leader

Postdoctoral fellow
10% ZAP
Kidney disease

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Roberto Fernandez Acosta, PhD

Postdoctoral fellow

Ferroptosis
Epigenetics

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Sylvina da Silva Fernandes

PhD Student

Ferroptosis
Chronic interstitial nephritis

Astrid Van den Branden 2

Astrid Van den Branden

PhD student

Ferroptosis
Chronic kidney disease

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Geraldine Veeckmans

PhD student

Ferroptosis
Ischemia/reperfusion injury

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Magali Walravens

PhD student

Ferroptosis
Mechanism lipid peroxidation

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Saar Adriaensen

PhD Student

Endothelial cells
Vascular calcification

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Elien Van Campen

PhD student

Nephrectomy
Regeneration

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Cyril Willemart

PhD student

Precision medicine 2.0 diagnostics
Nanopore episequencing cfDNA
Critical illness

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Tom Stroobants

PhD student

Precision medicin @ICU
Cell death intervention

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Ruben Van Hoyweghen

PhD student

Ferroptosis
Acute kidney injury

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Imke Winkelmans

PhD Student

Ferroptosis
Multiple sclerosis

2007 Hilde Geryl MR

Hilde Geryl

Technician

Experimental surgery
Bone histomorphometry
Biochemical analysis

2013 Geert Dams

Geert Dams

Technician

Experimental surgery
Animal follow-up
Bone histomorphometry

Former lab members
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Ine Koeken

PhD student

Ferroptosis
Anti-cancer therapeutics

2007 Ludwig Lamberts MR

Ludwig Lamberts

Technician

Biomedical Laboratory
Spectrometric Analyses

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Cedric Peleman

Phd student

Ferroptosis
Nonalcoholic fatty liver disease

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Behrouz Hassannia, PhD

Teamleader

Ferroptosis
Anti-cancer therapeutics

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Emily Van San, PhD

Postdoctoral fellow

Ferroptosis
Multiple sclerosis

Britt

Britt Opdebeeck, PhD

Postdoctoral fellow

Mechanisms of vascular calcification

2007 Rita Marynissen MR

Rita Marinyssen

Technician

Administration
Biochemical analysis

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Lies Moonen

PhD student

Nephrectomy induced repair

2017 Gerd 5416 MR

Gerd Schreurs

PhD student

Toxin induced nephropathy

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Geoffrey Van Den Bergh

PhD student

Arterial stiffness in vascular calcification

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Raphaëlle Corremans

PhD student

Metformin
Chronic kidney disease

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Claudina Perez Novo, PhD

Postdoctoral fellow

Ferroptosis
Anti-cancer therapeutics

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Bartosz Wiernicki

PhD student

Ferroptosis
Immunogenicity

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Samya Van Coillie

PhD student

Ferroptosis
Multi organ failure

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Sze Men Choi

Technician

Experimental surgery
Mouse manager
Standard lab analysis

2005 Geert Behets MR

Geert Behets, PhD

Teamleader

Postdoctoral fellow
Bone histomorphometry

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Dirk De Weerdt

Graphical support

principal investigator / PhD

Publications

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Patents

Number Name Date
US9862678, EP3218357 3,4-diaminobenzenesulfonamide derivatives for inhibiting cell death 2014-11-14
EP3749645, CN112105601, US20210094909 3-(benzylamino)-4-(cyclohexylamino)-n-(2-(piperazin-1-yl)ethyl)benzenesulfonamide derivatives and related ferrostatin-1 analogues as cell death inhibitors for treating e.g. stroke 2018-02-07
WO2015110346, US9919048 Targeting of interleukin-1 and -18 signaling in treatment of septic shock 2014-01-21
EP4590667, US19/113,145 Phenothiazine-based new ferroptosis inhibitors 2022-09-21
EP24187618 Novel ferroptosis inhibitors - 2024 016 Ferropcam 2024-07-10
EP24187620 Novel ferroptosis inhibitors - 2024 017 Alferopcom 2024-07-10
EP24187621.8 Novel ferroptosis inhibitors - 2024 018 Oxaferropcom 2024-07-10